Vitamin B12 (Cobalamin)

The Vitamin B12 Test measures the amount of vitamin B12 (cobalamin) in your blood. Vitamin B12 is essential for the production of red blood cells, nerve function, and DNA synthesis. A deficiency can lead to anemia, fatigue, and nerve damage.

• To detect vitamin B12 deficiency

• To diagnose pernicious anemia or other types of anemia

• To investigate symptoms like:

  • Fatigue

  • Tingling or numbness

  • Memory issues or confusion

  • Weakness or balance problems

• To monitor B12 levels during treatment or supplementation

Sample Required:
A blood sample

Fasting Required:

Fasting for 8–12 hours is often recommended for more accurate results.

• Low B12 levels may indicate:

  • Poor dietary intake (especially in vegetarians/vegans)

  • Malabsorption issues (e.g., in pernicious anemia, gastric bypass, or chronic gastritis)

  • Chronic alcohol use or certain medications (e.g., metformin, PPIs)

• High B12 levels are rare but may occur with liver disease, leukemia, or excessive supplementation.